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Tag: Saliva Testing

Our Partner Salimetrics LLC announced this week the launch of a Salivary Oxytocin Assay which we are pleased to report will be made available from Stratech Scientific here in Sydney Australia. Oxytocin is part of a highly complex psychological and biological system that underpins many of the archetypal human emotions and guides social interactions. Oxytocin exists as a cyclic active molecule and also in a pool with disulfides linked to other proteins. By using monoclonal antibody depletion experiments, Salimetrics was able to show that the...

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Tear Fluid SIgA as a Noninvasive Biomarker of Mucosal Immunity and Common Cold Risk. Hanstock HG1, Walsh NP, Edwards JP, Fortes MB, Cosby SL, Nugent A, Curran T, Coyle PV, Ward MD, Yong XH. Author information ABSTRACT PURPOSE: Research has not convincingly demonstrated the utility of saliva secretory immunoglobulin-A (SIgA) as a biomarker of upper respiratory tract infection (URTI) risk, and disagreement exists about the influence of heavy exercise ("open-window theory") and dehydration on saliva SIgA. Prompted by the search for viable alternatives, we compared...

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A recent study shows better assays and better labs are consistently producing better salivary bioscience study data. The research team analyzed salivary cortisol measurement error between established-qualified international academic-research laboratories using Salimetrics Assays. A new study published in BioMed Central Research Notes shows that using an established-qualified lab provides the best opportunity for consistent, reproducible data. Dr. Calvi and collaborators explored the possibility that inconsistent findings due to variations in assay performance from different laboratories may contribute to unsystematic error in salivary measurements, specifically for...

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A revolution in PCR. Sixteen PCR machines in one. With Minicube PCR, you’ll be able to run up to 16 different PCR protocols asynchronously at the same time. Each of the Minicube PCR’s 16 wells is its own precisely controlled temperature zone. The individual control of each well provides complete flexibility that will change the way you work. Imagine running protocols on 8 tubes while incubating 8 other tubes at 8 different temperatures – adding them to the Minicube PCR on the fly  

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Salivary alpha-amylase (sAA) is a surrogate measure of the autonomic/sympathetic nervous system (ANS) component of the stress response (see Granger et al., 2007; Nater et al., 2009). What may be surprising to you is the rapid pace that salivary alpha-amylase publications have appeared throughout mainstream scientific literature. The number of salivary alpha-amylase-focused articles has increased 213% since 2005, and continues to increase year on year (see figure below) Impact and Scientific Critical Mass of Salivary Alpha-Amylase The integration of salivary alpha-amylase as a marker of...

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Salivary markers of inflammation in response to acute stress. Slavish DC1, Graham-Engeland JE2, Smyth JM3, Engeland CG4. Author information The Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802, United States. The Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802, United States. Electronic address: jeg32@psu.edu. The Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802, United States; Penn State Milton S. Hershey Medical Center, The Pennsylvania State University, University Park, PA 16802, United States. The...

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All of our immunoassays (apart from alpha-amylase) are competitive immunoassays, meaning that the signal obtained is indirectly proportional to the concentration of the analyte. The higher the concentration of the molecule in the sample, the weaker the signal will be. The following pictures will explain the steps of a competitive ELISA: Step 1: Antibodies specific to the analytes to be tested are coated to a microtitre plate. A mixture of your sample (including an unknown concentration of the desired analyte) and the desired analyte (conjugated...

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